NUMA1 protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.

Your Input:
nuclear mitotic apparatus protein 1; Highly abundant component of the nuclear matrix where it may serve a non-mitotic structural role, occupies the majority if the nuclear volume. Required for maintenance and establishment of the mitotic spindle poles, functionning as a tether linking bulk microtubules of the spindle to centrosomes. May be involved in coordination of the alignment of the mitotic spindle to the cellular polarity axis, which is a prerequisite for asymmetric cell divisions (2115 aa)
(Homo sapiens)
Predicted Functional Partners:
cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle by modu [...] (297 aa)
aurora kinase A; Mitotic serine/threonine kinases that contributes to the regulation of cell cy [...] (403 aa)
tubulin, gamma 1; Tubulin is the major constituent of microtubules. The gamma chain is found at [...] (451 aa)
RAE1 RNA export 1 homolog (S. pombe); Binds mRNA. May function in nucleocytoplasmic transport a [...] (368 aa)
neural precursor cell expressed, developmentally down-regulated 1; Required for mitosis progres [...] (667 aa)
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) (864 aa)
erythrocyte membrane protein band 4.1-like 1 (881 aa)
karyopherin (importin) beta 1; Functions in nuclear protein import, either in association with [...] (876 aa)
structural maintenance of chromosomes 3; Central component of cohesin, a complex required for c [...] (1217 aa)
cyclin B1; Essential for the control of the cell cycle at the G2/M (mitosis) transition (433 aa)
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