ipp-5 protein (Caenorhabditis elegans) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




confidence	evidence	actions	interactive	advanced	more	less	save

Your Input:
	ipp-5	ipp-5 encodes a type I inositol 5-phosphatase homolog. ipp-5 acts downstream of let-23 to negatively regulate IP3 signaling and is involved in spermathecal contractions during ovulation. an ipp-5--gfp transcriptional reporter is expressed in the adult distal spermatheca and weakly in the proximal sheath (409 aa)
		(Caenorhabditis elegans)
Predicted Functional Partners:
	plc-3	PhosphoLipase C family member (plc-3) (1299 aa)		•	•	0.908
	plc-4	R05G6.8 (751 aa)		•		0.899
	egl-8	egl-8 encodes a phospholipase C beta homolog that affects pharyngeal pumping, defecation, and a [...] (1431 aa)		•		0.899
	sem-5	sem-5 encodes a Src homology (SH) domain 2 and 3-containing protein, orthologous to human GRB2 [...] (228 aa)	•		•	0.480
	par-3	par-3 encodes a PDZ domain-containing protein orthologous to mammalian atypical PKC isotype-spe [...] (1379 aa)			•	0.440
	let-413	let-413 encodes a protein with strong similarity to human ERBIN, rat DENSIN, Drosophila SCRIB a [...] (699 aa)			•	0.420
	dlg-1	dlg-1 encodes a MAGUK protein, orthologous to Drosophila disks large, that is physically locate [...] (967 aa)			•	0.414
	ajm-1	ajm-1 encodes a member of the apical junction molecule class that is required for correct elong [...] (1480 aa)			•	0.414
	F30A10.6	F30A10.6 (591 aa)			•	0.406
	itr-1	itr-1 encodes a putative inositol (1,4,5) trisphosphate receptor that affects the defecation cy [...] (2892 aa)			•	0.401

Views:

Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

required confidence (score):

interactors shown:

or custom value:

or custom limit:

additional (white) nodes		or: network depth