fabH protein (Clostridium difficile) - STRING interaction network

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	fabH	3-oxoacyl-[acyl-carrier-protein] synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and/or straight-chain of fatty acids (By similarity) (328 aa)
		(Clostridium difficile)
Predicted Functional Partners:
	fabD	Malonyl CoA-acyl carrier protein transacylase (316 aa)	•	•	•		•	•	0.999
	fabF	3-oxoacyl-[acyl-carrier-protein] synthase II (412 aa)	•	•			•	•	0.998
	fabG	3-oxoacyl-[acyl-carrier protein] reductase (249 aa)	•	•			•	•	0.993
	plsX	Fatty acid/phospholipid synthesis protein plsX; Probably involved in fatty acid or phospholipid [...] (340 aa)	•		•			•	0.991
	accD	Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzy [...] (284 aa)	•				•	•	0.967
	accA	Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenz [...] (314 aa)	•				•	•	0.960
	CD1183	Acyl carrier protein (74 aa)	•			•	•	•	0.951
	fabZ	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; Involved in saturated fatty acids bio [...] (142 aa)	•	•	•			•	0.951
	fabK	Trans-2-enoyl-ACP reductase (309 aa)	•				•		0.929
	CD1062	Acyl carrier protein (75 aa)	•			•	•	•	0.912

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Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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