aceK protein (Burkholderia cenocepacia 1054)

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	aceK	Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity) (605 aa)
		(Burkholderia cenocepacia 1054)
Predicted Functional Partners:
	xylA	Xylose isomerase (440 aa)	•	0.899
	Bcen_4568	riboflavin synthase, alpha subunit (237 aa)	•	0.899
	Bcen_4514	Thiamine monophosphate synthase (194 aa)	•	0.899
	Bcen_2694	Thiamine-phosphate pyrophosphorylase (375 aa)	•	0.899
	Bcen_1842	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis [...] (360 aa)	•	0.899
	Bcen_1060	PfkB (312 aa)	•	0.899
	Bcen_0854	UDP-N-acetylglucosamine 2-epimerase (405 aa)	•	0.899
	Bcen_0481	5-amino-6-(5-phosphoribosylamino)uracil reductase / diaminohydroxyphosphoribosylaminopyrimidine [...] (373 aa)	•	0.899
	Bcen_0480	Riboflavin synthase, alpha subunit (209 aa)	•	0.899
	ribH	6,7-dimethyl-8-ribityllumazine synthase; Riboflavin synthase is a bifunctional enzyme complex c [...] (171 aa)	•	0.899

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Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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