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This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
guaC
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity) (325 aa)
(Helicobacter pylori HPAG1)
Predicted Functional Partners:
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (By similarity) (508 aa)
• •• •• 0.979
purA
Putative uncharacterized protein; Plays an important role in the de novo pathway of purine nucl [...] (411 aa)
•    •• 0.969
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of A [...] (179 aa)
     •• 0.949
guaB
Inosine-5'-monophosphate dehydrogenase (481 aa)
  •• •••0.919
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP (By similarity) (206 aa)
     •• 0.911
HP_1490
putative integral membrane protein with a TlyC-like hemolysin domain (445 aa)
     •  0.899
surE
5'-nucleotidase surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophospha [...] (267 aa)
     •  0.899
HP_0735
Xanthine guanine phosphoribosyl transferase (Gpt) (153 aa)
     •  0.899
HP_0853
ABC transporter, ATP-binding protein (YheS) (533 aa)
•       0.602
HPAG1_0836
Putative uncharacterized protein (179 aa)
•       0.602
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.
Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:
additional (white) nodes         or: network depth