aceK protein (Escherichia coli UTI89) - STRING interaction network

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	aceK	Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity) (574 aa)
		(Escherichia coli UTI89)
Predicted Functional Partners:
	aceA	Isocitrate lyase (439 aa)	•	•		•	0.932
	aceB	Malate synthase A (539 aa)	•			•	0.905
	yihV	hypothetical sugar kinase YihV (315 aa)			•		0.899
	rffE	UDP-N-acetylglucosamine 2-epimerase (390 aa)			•		0.899
	xylA	Xylose isomerase (444 aa)			•		0.899
	thiE	Thiamin phosphate synthase (Thiamin phosphate pyrophosphorylase); Condenses 4-methyl-5-(beta-hy [...] (212 aa)			•		0.899
	nanA	N-acetylneuraminate lyase; Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to f [...] (297 aa)			•		0.899
	neuB	Sialic acid synthase NeuB (346 aa)			•		0.899
	neuC	Polysialic acid biosynthesis protein P7; May be involved in the synthesis of polysialic acid (P [...] (391 aa)			•		0.899
	gutB	Sorbitol dehydrogenase (364 aa)			•		0.899

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Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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