version_number_image
 
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
pdhA
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components- pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity) (326 aa)
(Rickettsia bellii RML)
Predicted Functional Partners:
pdhB
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes [...] (325 aa)
 0.999
pdhC
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The [...] (418 aa)
  0.999
lpdA2
Dihydrolipoamide dehydrogenase (459 aa)
    0.996
lpdA1
Dihydrolipoamide dehydrogenase (459 aa)
     0.989
tme
Malate oxidoreductase and phosphate acetyltransferase (765 aa)
      0.905
ppdK
Pyruvate, phosphate dikinase; Catalyzes the reversible phosphorylation of pyruvate and phosphat [...] (878 aa)
       0.899
sucB
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase compl [...] (400 aa)
   0.877
lipA
Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and [...] (355 aa)
     0.862
sdhC
Succinate dehydrogenase cytochrome b556 subunit; Mono-heme cytochrome of the succinate dehydrog [...] (125 aa)
      0.844
sdhB
Succinate dehydrogenase iron-sulfur subunit (261 aa)
      0.814
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes         or: network depth