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This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
cyp51
Probable cytochrome P450 51; Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol (By similarity) (466 aa)
(Dictyostelium discoideum)
Predicted Functional Partners:
cas1
Cycloartenol synthase; Converts oxidosqualene to cycloartenol (in vitro) (703 aa)
   •••• 0.987
erg24
Delta(14)-sterol reductase; Reduces the C14=C15 double bond of 4,4-dimethyl- cholesta-8,14,24-t [...] (462 aa)
    ••• 0.962
DDB_0191312
ERG4/ERG24 ergosterol biosynthesis protein family protein (381 aa)
    ••• 0.945
fdfT
farnesyl-diphosphate farnesyltransferase (416 aa)
   •• • 0.789
smt1
Probable cycloartenol-C-24-methyltransferase 1; Catalyzes the methyl transfer from S-adenosyl-m [...] (354 aa)
    • • 0.670
sqle
Squalene monooxygenase (502 aa)
    • • 0.606
erg2
Protein erg2 homolog; May function in lipid transport from the endoplasmic reticulum and be inv [...] (233 aa)
   ••   0.606
DDB_0233059
3beta-hydroxysteroid dehydrogenase (349 aa)
    • • 0.603
DDBDRAFT_0190553
Putative uncharacterized protein (270 aa)
   •• • 0.557
DDBDRAFT_0204917
Putative uncharacterized protein (150 aa)
    • • 0.486
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.
Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:
additional (white) nodes         or: network depth