mutM protein (Saccharophagus degradans)

STRING 9.05

mutM protein (Saccharophagus degradans) - STRING network view

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	mutM	formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) (271 aa)
		(Saccharophagus degradans)
Predicted Functional Partners:
	coaE	phosphoribosylglycinamide formyltransferase; Catalyzes the phosphorylation of the 3'-hydroxyl g [...] (203 aa)	•	•	•	0.978
	Sde_0073	DNA polymerase I (926 aa)	•		•	0.952
	Sde_0337	A/G-specific DNA-adenine glycosylase (355 aa)	•		•	0.932
	Sde_3599	CheW protein (181 aa)	•		•	0.890
	Sde_2243	RNAse III (226 aa)	•		•	0.877
	Sde_1106	DNA polymerase III subunit alpha (1173 aa)	•		•	0.867
	Sde_1218	uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of mis [...] (218 aa)	•		•	0.853
	recA	recombinase A; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the A [...] (348 aa)	•		•	0.851
	Sde_1060	primary replicative DNA helicase (488 aa)	•		•	0.842
	Sde_2507	DNA-directed DNA polymerase (358 aa)	•		•	0.839

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