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This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
aceK
Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity) (615 aa)
(Rhodoferax ferrireducens)
Predicted Functional Partners:
ribH
6,7-dimethyl-8-ribityllumazine synthase; Riboflavin synthase is a bifunctional enzyme complex c [...] (157 aa)
       0.899
Rfer_2667
Riboflavin synthase, alpha subunit (231 aa)
       0.899
Rfer_2666
Diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil [...] (377 aa)
       0.899
Rfer_2611
Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis [...] (362 aa)
       0.899
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophos [...] (219 aa)
       0.899
Rfer_2467
Thiamine-phosphate diphosphorylase (312 aa)
       0.899
Rfer_1904
PfkB (336 aa)
       0.899
Rfer_0663
UDP-N-acetylglucosamine 2-epimerase (398 aa)
       0.899
Rfer_0529
Thiamine-monophosphate kinase (335 aa)
       0.899
Rfer_1335
Isocitrate lyase (439 aa)
     0.807
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes         or: network depth