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  PIK3CG protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
PIK3CG
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K); 3-phosphorylates the cellular phosphoinositide PtdIns- 4,5-biphosphate (PtdIns(4,5)P2) to produce PtdIns-3, 4,5- triiphosphate (PtdIns(3,4,5)P3). Links G-protein coupled receptor activation to the secondary messenger PtdIns(3,4,5)P3 production (1102 aa)
(Homo sapiens)
Predicted Functional Partners:
AKT1
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (Protein kinase B) (PKB) [...] (480 aa)
     •• 0.996
PIK3R5
Phosphoinositide 3-kinase regulatory subunit 5 (PI3-kinase regulatory subunit 5) (PI3-kinase p1 [...] (880 aa)
    ••• 0.996
PTEN
Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual- specificity protein phosphatas [...] (403 aa)
     •• 0.994
HRAS
GTPase HRas precursor (Transforming protein p21) (p21ras) (H-Ras-1) (c-H-ras) (Ha-Ras); Ras pro [...] (273 aa)
    ••• 0.994
C17orf38
Phosphoinositide 3-kinase regulatory subunit 6 (Phosphoinositide 3- kinase gamma adapter protei [...] (752 aa)
    ••• 0.987
LYN
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (582 aa)
    ••• 0.980
PIK3R1
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3 [...] (724 aa)
     •• 0.979
INS
Insulin precursor [Contains- Insulin B chain; Insulin A chain]; Insulin decreases blood glucose [...] (110 aa)
     •• 0.973
RASD1
Dexamethasone-induced Ras-related protein 1 precursor (Activator of G- protein signaling 1) (281 aa)
      • 0.971
SRC
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src) (542 aa)
     •• 0.970
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.
Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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