mutM protein (Rhodospirillum rubrum)

STRING 9.05

mutM protein (Rhodospirillum rubrum) - STRING network view

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	mutM	formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) (281 aa)
		(Rhodospirillum rubrum)
Predicted Functional Partners:
	Rru_A3514	DNA polymerase A (924 aa)	•			•	0.951
	coaE	dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzy [...] (229 aa)	•	•		•	0.941
	Rru_A3251	A/G-specific DNA-adenine glycosylase (359 aa)	•			•	0.928
	Rru_A1582	DNA polymerase III subunit alpha (1170 aa)	•			•	0.909
	coaD	phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- [...] (172 aa)	•			•	0.880
	Rru_A1852	RNAse III (221 aa)	•			•	0.863
	recA	recombinase A; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the A [...] (366 aa)	•			•	0.849
	Rru_A0410	DnaB helicase (507 aa)	•			•	0.834
	uvrC	excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing o [...] (639 aa)			•	•	0.826
	Rru_A3530	DNA polymerase IV (421 aa)	•			•	0.825

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