lexA protein (Brucella melitensis 2308) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




confidence	evidence	actions	interactive	advanced	more	less	save

Your Input:
	lexA	LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, recA interacts with lexA causing an autocatalytic cleavage which disrupts the DNA-binding part of lexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) (240 aa)
		(Brucella melitensis 2308)
Predicted Functional Partners:
	recA	Protein recA; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the AT [...] (361 aa)	•	•	•	•	0.948
	dnaE2	Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesi [...] (1077 aa)	•			•	0.782
	panC	Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dep [...] (293 aa)	•				0.610
	gcp	Probable O-sialoglycoprotein endopeptidase (359 aa)	•				0.607
	metG	Aminoacyl-tRNA synthetase, class I-Aminoacyl-tRNA synthetase, class Ia-Methionyl-tRNA synthetas [...] (515 aa)	•				0.597
	BAB2_0366	Sugar-phosphate isomerases, RpiB/LacA/LacB family (151 aa)	•				0.596
	uvrB	UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of D [...] (940 aa)	•			•	0.591
	gltX2	Glutamyl-tRNA synthetase, class Ic-Arginyl-tRNA synthetase, class Ic-Aminoacyl-tRNA synthetase, [...] (473 aa)	•				0.578
	BAB2_0625	UMUC-like DNA-repair protein (445 aa)	•			•	0.525
	BAB1_0456	Histone deacetylase family protein (337 aa)	•				0.519

Views:

Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

required confidence (score):

interactors shown:

or custom value:

or custom limit:

additional (white) nodes		or: network depth