thyA protein (Brucella melitensis 2308) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




confidence	evidence	actions	interactive	advanced	more	less	save

Your Input:
	thyA	Thymidylate synthase; Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) (264 aa)
		(Brucella melitensis 2308)
Predicted Functional Partners:
	folA	FolA, dihydrofolate reductase (172 aa)	•	•	•		•	•	0.999
	glyA	Serine hydroxymethyltransferase; Interconversion of serine and glycine (438 aa)	•				•	•	0.967
	dut	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabol [...] (157 aa)					•	•	0.963
	tmk	Thymidylate kinase-ATP/GTP-binding site motif A (P-loop) (211 aa)					•	•	0.952
	folD	Bifunctional protein folD; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-m [...] (299 aa)	•			•	•	•	0.948
	gcvT	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine (367 aa)	•				•		0.937
	metF	Methylenetetrahydrofolate reductase-5,10-methylenetetrahydrofolate reductase (303 aa)					•	•	0.925
	gcvP	Glycine dehydrogenase [decarboxylating]; The glycine cleavage system catalyzes the degradation [...] (932 aa)					•		0.899
	surE	5'-nucleotidase surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophospha [...] (255 aa)					•		0.899
	nrdE	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Cata [...] (713 aa)	•		•			•	0.872

Views:

Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

required confidence (score):

interactors shown:

or custom value:

or custom limit:

additional (white) nodes		or: network depth