stxA protein (Shigella dysenteriae) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




confidence	evidence	actions	interactive	advanced	more	less	save

Your Input:
	stxA	Shiga toxin subunit A; The A subunit is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits. After endocytosis, the A subnit is cleaved by furin in two fragments, A1 and A2- A1 is the catalytically active fragment, and A2 is essential for holotoxin assembly with the B subunits (315 aa)
		(Shigella dysenteriae)
Predicted Functional Partners:
	stxB	Shiga toxin subunit B; The B subunit is responsible for the binding of the holotoxin to specifi [...] (89 aa)	•	•	0.902
	SDY_1388	IS600 ORF2 (144 aa)	•		0.514
	SDY_1387	IS600 ORF2 (138 aa)	•		0.458
	SDY_1386	IS600 ORF1 (100 aa)	•		0.401

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Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

required confidence (score):

interactors shown:

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additional (white) nodes		or: network depth