aceK protein (Burkholderia pseudomallei 1710b)

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	aceK	Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity) (603 aa)
		(Burkholderia pseudomallei 1710b)
Predicted Functional Partners:
	wecB	UDP-N-acetylglucosamine 2-epimerase (404 aa)	•	0.899
	BPSS1796	DGTP-pyrophosphohydrolase; thiamine phosphate synthase (196 aa)	•	0.899
	BPSS1216	DGTP-pyrophosphohydrolase; thiamine phosphate synthase (212 aa)	•	0.899
	BPSS1125	Riboflavin biosynthesis protein RibD (454 aa)	•	0.899
	BPSS1103	thiaminase I precursor (585 aa)	•	0.899
	thiE	Thiamine-phosphate pyrophosphorylase (367 aa)	•	0.899
	thiL	Thiamine-monophosphate kinase (333 aa)	•	0.899
	ribH	6,7-dimethyl-8-ribityllumazine synthase; Riboflavin synthase is a bifunctional enzyme complex c [...] (191 aa)	•	0.899
	ribE	Riboflavin synthase, alpha subunit (204 aa)	•	0.899
	BURPS1710b_3100	Riboflavin biosynthesis protein RibD (378 aa)	•	0.899

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Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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