Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but at higher resolution
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KPNB1 | NUP153 | ENSBTAP00000008650 | ENSBTAP00000067342 | Karyopherin subunit beta 1. | Nucleoporin 153. | 0.966 |
KPNB1 | RAN | ENSBTAP00000008650 | ENSBTAP00000067034 | Karyopherin subunit beta 1. | GTP-binding nuclear protein Ran; GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs. Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis. Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP- bound RAN and release them upon direct interaction with GTP-bound RAN, while export receptors behave in the opposite way. Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment [...] | 0.954 |
KPNB1 | RANBP1 | ENSBTAP00000008650 | ENSBTAP00000008744 | Karyopherin subunit beta 1. | Ran-specific GTPase-activating protein; Plays a role in RAN-dependent nucleocytoplasmic transport. Alleviates the TNPO1-dependent inhibition of RAN GTPase activity and mediates the dissociation of RAN from proteins involved in transport into the nucleus (By similarity). Induces a conformation change in the complex formed by XPO1 and RAN that triggers the release of the nuclear export signal of cargo proteins (By similarity). Promotes the disassembly of the complex formed by RAN and importin beta. Promotes dissociation of RAN from a complex with KPNA2 and CSE1L (By similarity). Required [...] | 0.859 |
KPNB1 | RANBP2 | ENSBTAP00000008650 | ENSBTAP00000060769 | Karyopherin subunit beta 1. | E3 SUMO-protein ligase RanBP2; E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Binds single- stranded RNA (in vitro). May bind DNA. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin- 1. Sumoylates PML at 'Lys-490' which is essential for the proper assembly of PML-NB. Recruits BICD2 to the nuclear envelope and cytoplasmic stacks of nuclear pore compl [...] | 0.950 |
KPNB1 | RANGAP1 | ENSBTAP00000008650 | ENSBTAP00000012125 | Karyopherin subunit beta 1. | Ran GTPase activating protein 1. | 0.843 |
KPNB1 | RCC1 | ENSBTAP00000008650 | ENSBTAP00000061750 | Karyopherin subunit beta 1. | Regulator of chromosome condensation 1. | 0.831 |
KPNB1 | TNPO1 | ENSBTAP00000008650 | ENSBTAP00000010491 | Karyopherin subunit beta 1. | Transportin-1; Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis [...] | 0.784 |
KPNB1 | XPO1 | ENSBTAP00000008650 | ENSBTAP00000017629 | Karyopherin subunit beta 1. | Exportin 1. | 0.898 |
KPNB1 | XPO5 | ENSBTAP00000008650 | ENSBTAP00000073577 | Karyopherin subunit beta 1. | Exportin 5. | 0.740 |
KPNB1 | XPOT | ENSBTAP00000008650 | ENSBTAP00000069261 | Karyopherin subunit beta 1. | Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family. | 0.676 |
NUP153 | KPNB1 | ENSBTAP00000067342 | ENSBTAP00000008650 | Nucleoporin 153. | Karyopherin subunit beta 1. | 0.966 |
NUP153 | RAN | ENSBTAP00000067342 | ENSBTAP00000067034 | Nucleoporin 153. | GTP-binding nuclear protein Ran; GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs. Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis. Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP- bound RAN and release them upon direct interaction with GTP-bound RAN, while export receptors behave in the opposite way. Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment [...] | 0.986 |
NUP153 | RANBP1 | ENSBTAP00000067342 | ENSBTAP00000008744 | Nucleoporin 153. | Ran-specific GTPase-activating protein; Plays a role in RAN-dependent nucleocytoplasmic transport. Alleviates the TNPO1-dependent inhibition of RAN GTPase activity and mediates the dissociation of RAN from proteins involved in transport into the nucleus (By similarity). Induces a conformation change in the complex formed by XPO1 and RAN that triggers the release of the nuclear export signal of cargo proteins (By similarity). Promotes the disassembly of the complex formed by RAN and importin beta. Promotes dissociation of RAN from a complex with KPNA2 and CSE1L (By similarity). Required [...] | 0.743 |
NUP153 | RANBP2 | ENSBTAP00000067342 | ENSBTAP00000060769 | Nucleoporin 153. | E3 SUMO-protein ligase RanBP2; E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Binds single- stranded RNA (in vitro). May bind DNA. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin- 1. Sumoylates PML at 'Lys-490' which is essential for the proper assembly of PML-NB. Recruits BICD2 to the nuclear envelope and cytoplasmic stacks of nuclear pore compl [...] | 0.982 |
NUP153 | RANGAP1 | ENSBTAP00000067342 | ENSBTAP00000012125 | Nucleoporin 153. | Ran GTPase activating protein 1. | 0.874 |
NUP153 | RCC1 | ENSBTAP00000067342 | ENSBTAP00000061750 | Nucleoporin 153. | Regulator of chromosome condensation 1. | 0.602 |
NUP153 | TNPO1 | ENSBTAP00000067342 | ENSBTAP00000010491 | Nucleoporin 153. | Transportin-1; Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis [...] | 0.808 |
NUP153 | XPO1 | ENSBTAP00000067342 | ENSBTAP00000017629 | Nucleoporin 153. | Exportin 1. | 0.678 |
NUP153 | XPO5 | ENSBTAP00000067342 | ENSBTAP00000073577 | Nucleoporin 153. | Exportin 5. | 0.557 |
NUP153 | XPOT | ENSBTAP00000067342 | ENSBTAP00000069261 | Nucleoporin 153. | Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family. | 0.411 |
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