Sfrp2 protein (Mus musculus) - STRING interaction network

Sfrp2 protein (Mus musculus) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




confidence	evidence	actions	interactive	advanced	more	less	save

Your Input:
	Sfrp2	secreted frizzled-related protein 2; Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis (295 aa)
		(Mus musculus)
Predicted Functional Partners:
	Wnt3a	wingless-related MMTV integration site 3A; Ligand for members of the frizzled family of seven t [...] (352 aa)		•	•	0.985
	ENSMUSG00000036856	wingless-related MMTV integration site 4; Ligand for members of the frizzled family of seven tr [...] (351 aa)	•	•	•	0.946
	Wnt6	wingless-related MMTV integration site 6; Ligand for members of the frizzled family of seven tr [...] (364 aa)		•	•	0.945
	Wnt1	wingless-related MMTV integration site 1; Ligand for members of the frizzled family of seven tr [...] (370 aa)		•	•	0.934
	Wnt5a	wingless-related MMTV integration site 5A; Ligand for members of the frizzled family of seven t [...] (380 aa)		•	•	0.930
	Pax6	paired box gene 6; Transcription factor with important functions in the development of the eye, [...] (467 aa)			•	0.917
	Wnt7b	wingless-related MMTV integration site 7B; Ligand for members of the frizzled family of seven t [...] (471 aa)		•	•	0.897
	Cdh1	cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interac [...] (884 aa)			•	0.877
	Wnt9a	wingless-type MMTV integration site 9A; Ligand for members of the frizzled family of seven tran [...] (365 aa)		•	•	0.875
	Ctnnb1	catenin (cadherin associated protein), beta 1; Involved in the regulation of cell adhesion and [...] (781 aa)			•	0.865

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Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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