rtcA protein (Methanosarcina barkeri) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




confidence	evidence	actions	interactive	advanced	more	less	save

Your Input:
	rtcA	Probable RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps- (A) adenylation of the enzyme by ATP; (B) the enzyme acts on RNA-N3'P to produce RNA-N3'PP5'A; (C) a non catalytic nucleophilic attack by the adjacent 2'hydroxyl on the phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity) (331 aa)
		(Methanosarcina barkeri)
Predicted Functional Partners:
	Mbar_A1252	Putative uncharacterized protein (500 aa)	•	•	•	0.859
	Mbar_A3172	Ribose-5-phosphate isomerase (232 aa)			•	0.746
	Mbar_A1251	UPF0211 protein Mbar_A1251 (146 aa)	•	•		0.692
	Mbar_A0138	Putative uncharacterized protein (166 aa)	•			0.668
	Mbar_A1642	DNA polymerase X family / putative histidinol phosphatase (584 aa)	•			0.667
	rpoL	DNA-directed RNA polymerase subunit L; DNA-dependent RNA polymerase catalyzes the transcription [...] (92 aa)	•			0.665
	Mbar_A3650	transcription factor homologous to NACalpha-BTF3 (120 aa)	•			0.652
	Mbar_A0363	Ribose-phosphate pyrophosphokinase (283 aa)	•			0.648
	Mbar_A1635	Methyltransferase (197 aa)	•			0.628
	Mbar_A3470	Putative uncharacterized protein (166 aa)	•			0.623

Views:

Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

required confidence (score):

interactors shown:

or custom value:

or custom limit:

additional (white) nodes		or: network depth