aceK protein (Colwellia psychrerythraea) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




confidence	evidence	actions	interactive	advanced	more	less	save

Your Input:
	aceK	Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity) (589 aa)
		(Colwellia psychrerythraea)
Predicted Functional Partners:
	CPS_3659	Putative nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the [...] (392 aa)			•		0.899
	CPS_2648	Carbohydrate kinase, PfkB family (336 aa)			•		0.899
	thiL	Thiamine-monophosphate kinase (320 aa)			•		0.899
	ribH	6,7-dimethyl-8-ribityllumazine synthase; Riboflavin synthase is a bifunctional enzyme complex c [...] (154 aa)			•		0.899
	ribE1	Riboflavin synthase, alpha subunit (232 aa)			•		0.899
	ribD	Riboflavin biosynthesis protein RibD (389 aa)			•		0.899
	thiDE	phosphomethylpyrimidine kinase/thiamin-phosphate pyrophosphorylase (529 aa)			•		0.899
	icd	isocitrate dehydrogenase, NADP-dependent (416 aa)	•	•		•	0.688
	CPS_3483	Carbonic anhydrase (199 aa)	•				0.650
	CPS_3761	Putative uncharacterized protein (328 aa)		•			0.610

Views:

Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

required confidence (score):

interactors shown:

or custom value:

or custom limit:

additional (white) nodes		or: network depth