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This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
aceK
Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity) (573 aa)
(Pseudomonas fluorescens Pf5)
Predicted Functional Partners:
PFL_5522
Riboflavin biosynthesis protein RibD (377 aa)
       0.899
PFL_5521
Riboflavin synthase, alpha subunit (220 aa)
       0.899
PFL_5519
6,7-dimethyl-8-ribityllumazine synthase; Riboflavin synthase is a bifunctional enzyme complex c [...] (158 aa)
       0.899
thiL
Thiamine-monophosphate kinase (321 aa)
       0.899
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophos [...] (207 aa)
       0.899
PFL_5107
UDP-N-acetylglucosamine 2-epimerase (375 aa)
       0.899
PFL_4779
Mutator mutT protein, putative (339 aa)
       0.899
PFL_4508
6,7-dimethyl-8-ribityllumazine synthase; Riboflavin synthase is a bifunctional enzyme complex c [...] (169 aa)
       0.899
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis [...] (351 aa)
       0.899
PFL_3595
UDP-N-acetylglucosamine 2-epimerase (383 aa)
       0.899
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
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additional (white) nodes         or: network depth