PKM2 protein (Homo sapiens) - STRING interaction network

PKM2 protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	PKM2	Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40) (Pyruvate kinase muscle isozyme) (Pyruvate kinase 2/3) (Cytosolic thyroid hormone-binding protein) (CTHBP) (THBP1); Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP (531 aa)
		(Homo sapiens)
Predicted Functional Partners:
	ENO1	Alpha-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Non- neural enolase) (NNE) (En [...] (434 aa)	•	•		•	•	0.976
	PC	Pyruvate carboxylase, mitochondrial precursor (EC 6.4.1.1) (Pyruvic carboxylase) (PCB); Pyruvat [...] (1178 aa)			•	•	•	0.972
	LDHA	L-lactate dehydrogenase A chain (EC 1.1.1.27) (LDH-A) (LDH muscle subunit) (LDH-M) (Proliferati [...] (332 aa)	•			•	•	0.968
	TPI1	Triosephosphate isomerase (EC 5.3.1.1) (TIM) (Triose-phosphate isomerase) (271 aa)	•			•	•	0.965
	AK1	Adenylate kinase isoenzyme 1 (EC 2.7.4.3) (ATP-AMP transphosphorylase) (AK1) (Myokinase); This [...] (210 aa)				•	•	0.965
	ITPA	Inosine triphosphate pyrophosphatase (EC 3.6.1.19) (ITPase) (Inosine triphosphatase) (Putative [...] (194 aa)				•	•	0.958
	LDHB	L-lactate dehydrogenase B chain (EC 1.1.1.27) (LDH-B) (LDH heart subunit) (LDH-H) (Renal carcin [...] (334 aa)	•			•	•	0.950
	ME1	NADP-dependent malic enzyme (EC 1.1.1.40) (NADP-ME) (Malic enzyme 1) (572 aa)				•	•	0.946
	ENO2	Gamma-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Neural enolase) (Neuron-specif [...] (434 aa)	•	•		•	•	0.946
	ENO3	Beta-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Muscle-specific enolase) (MSE) [...] (434 aa)	•	•		•	•	0.946

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Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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