STRINGSTRING
DDB_G0286481 DDB_G0286481 csnk2b csnk2b casK casK cprD cprD ssrp1 ssrp1 spt16 spt16 DDB0190597 DDB0190597 Nol6 Nol6 DDB0190166 DDB0190166 Wdr46 Wdr46 drg1 drg1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
DDB_G0286481Probable serine/threonine-protein kinase DDB_G0286481. (605 aa)    
Predicted Functional Partners:
csnk2b
Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.
   
 0.954
casK
Casein kinase II subunit alpha; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha chain contains the catalytic site; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CK2 subfamily.
  
  
 
0.902
cprD
Cysteine proteinase 4.
    
 
 0.827
ssrp1
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
    
 0.748
spt16
FACT complex subunit SPT16; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
   
 0.746
DDB0190597
RRP7 domain-containing protein.
   
 
 0.647
Nol6
Uncharacterized protein.
    
 
 0.618
DDB0190166
NUC153 domain-containing protein.
   
   0.575
Wdr46
WD_REPEATS_REGION domain-containing protein.
    
   0.546
drg1
Developmentally-regulated GTP-binding protein 1 homolog; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
   
   0.543
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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