PLCB2 protein (Homo sapiens) - STRING interaction network

PLCB2 protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	PLCB2	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-2) (PLC-beta-2); The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes (1188 aa)
		(Homo sapiens)
Predicted Functional Partners:
	GNAQ	Guanine nucleotide-binding protein G(q) subunit alpha (Guanine nucleotide-binding protein alpha [...] (359 aa)	•	•	•	0.987
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (T [...] (2671 aa)		•	•	0.969
	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 1 (Transducin beta chain 1); Gua [...] (340 aa)		•	•	0.962
	GNB5	Guanine nucleotide-binding protein subunit beta 5 (Transducin beta chain 5) (Gbeta5); Guanine n [...] (395 aa)		•	•	0.959
	MAPK14	Mitogen-activated protein kinase 14 (EC 2.7.11.24) (Mitogen-activated protein kinase p38 alpha) [...] (360 aa)	•	•	•	0.957
	SUCLG2	Succinyl-CoA ligase [GDP-forming] beta-chain, mitochondrial precursor (EC 6.2.1.4) (Succinyl-Co [...] (432 aa)			•	0.956
	GNB3	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 3 (Transducin beta chain 3); Gua [...] (340 aa)		•	•	0.949
	GNG13	Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-13 subunit precursor; Guanine nucleotid [...] (67 aa)		•	•	0.942
	GNAO1	Guanine nucleotide-binding protein G(o) subunit alpha 1; Guanine nucleotide-binding proteins (G [...] (354 aa)		•	•	0.939
	GNG2	Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit precursor (G gamma-I); Guanin [...] (71 aa)		•	•	0.930

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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