ABCC8 protein (Homo sapiens) - STRING interaction network

ABCC8 protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	ABCC8	ATP-binding cassette transporter sub-family C member 8 (Sulfonylurea receptor 1); Putative subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive K(+) channels and insulin release (1583 aa)
		(Homo sapiens)
Predicted Functional Partners:
	KCNJ11	ATP-sensitive inward rectifier potassium channel 11 (Potassium channel, inwardly rectifying sub [...] (390 aa)		•	•	•	0.999
	RAPGEF4	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) [...] (1010 aa)		•	•	•	0.982
	KCNJ8	ATP-sensitive inward rectifier potassium channel 8 (Potassium channel, inwardly rectifying subf [...] (424 aa)		•		•	0.981
	FOXA2	Hepatocyte nuclear factor 3-beta (HNF-3B) (Forkhead box protein A2); Transcription activator fo [...] (457 aa)			•	•	0.977
	INS	Insulin precursor [Contains- Insulin B chain; Insulin A chain]; Insulin decreases blood glucose [...] (110 aa)	•			•	0.966
	GCG	Glucagon precursor [Contains- Glicentin; Glicentin-related polypeptide (GRPP); Oxyntomodulin (O [...] (182 aa)				•	0.946
	GCK	Glucokinase (EC 2.7.1.2) (Hexokinase-4) (Hexokinase type IV) (HK IV) (HK4) (Hexokinase-D); Cata [...] (466 aa)				•	0.944
	PDX1	Pancreas/duodenum homeobox protein 1 (PDX-1) (Insulin promoter factor 1) (IPF-1) (Islet/duodenu [...] (283 aa)				•	0.925
	ENSA	Alpha-endosulfine (ARPP-19e); Endogenous ligand for sulfonylurea receptor. By inhibiting sulfon [...] (187 aa)		•		•	0.920
	SLC25A4	ADP/ATP translocase 1 (Adenine nucleotide translocator 1) (ANT 1) (ADP,ATP carrier protein 1) ( [...] (298 aa)			•	•	0.908

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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