STRINGSTRING
UGDH UGDH UXS1 UXS1 TGDS TGDS GALE GALE UGP2 UGP2 UGT1A1 UGT1A1 UGT2A1 UGT2A1 GALT GALT SMIM14 SMIM14 HAS2 HAS2 SECISBP2L SECISBP2L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
UGDHUDP-glucose 6-dehydrogenase; Catalyzes the formation of UDP-alpha-D-glucuronate, a constituent of complex glycosaminoglycans (By similarity). Required for the biosynthesis of chondroitin sulfate and heparan sulfate. Required for embryonic development via its role in the biosynthesis of glycosaminoglycans (By similarity). (494 aa)    
Predicted Functional Partners:
UXS1
UDP-glucuronate decarboxylase 1.
 0.994
TGDS
TDP-glucose 4,6-dehydratase.
  
  
 0.985
GALE
UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
  
 
 0.984
UGP2
UTP--glucose-1-phosphate uridylyltransferase.
   
 
 0.965
UGT1A1
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
     
 0.915
UGT2A1
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
     
 0.915
GALT
Galactose-1-phosphate uridylyltransferase; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
    
 0.884
SMIM14
Uncharacterized protein.
 
 
  
 0.862
HAS2
Hyaluronan synthase 2; Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation (By similarity); Belongs to the NodC/HAS family.
  
 
 0.835
SECISBP2L
SECIS binding protein 2 like.
  
 
 0.827
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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