MTHFR protein (Bos taurus) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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	MTHFR	Methylenetetrahydrofolate reductase (EC 1.5.1.20); Catalyzes the conversion of 5,10- methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co- substrate for homocysteine remethylation to methionine (By similarity) (655 aa)
		(Bos taurus)
Predicted Functional Partners:
	ms	Methionine synthase (EC 2.1.1.13) (5-methyltetrahydrofolate-- homocysteine methyltransferase) ( [...] (1255 aa)	•		•	•	0.987
	SHMT1	Serine hydroxymethyltransferase, cytosolic (EC 2.1.2.1) (Serine methylase) (Glycine hydroxymeth [...] (484 aa)			•	•	0.932
	SHMT2	Serine hydroxymethyltransferase, mitochondrial precursor (EC 2.1.2.1) (Serine methylase) (Glyci [...] (504 aa)			•	•	0.929
	AMT	Aminomethyltransferase, mitochondrial precursor (EC 2.1.2.10) (Glycine cleavage system T protei [...] (397 aa)	•		•		0.929
	GCSH	Glycine cleavage system H protein, mitochondrial precursor; The glycine cleavage system catalyz [...] (173 aa)	•		•		0.908
	ST6GALNAC2	hypothetical protein LOC511690 (347 aa)			•		0.899
	CTH	Cystathionine gamma-lyase (EC 4.4.1.1) (Gamma-cystathionase) (386 aa)	•	•		•	0.756
	MAT1A	hypothetical protein LOC541078; Catalyzes the formation of S-adenosylmethionine from methionine [...] (396 aa)	•			•	0.724
	CBS	CBS protein (492 aa)				•	0.669
	ELF5	ETS-related transcription factor Elf-5 (E74-like factor 5); Transcriptionally activator that ma [...] (255 aa)				•	0.651

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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