STRINGSTRING
arl6 arl6 arl6ip1 arl6ip1 bbs7 bbs7 bbs1 bbs1 bbs9 bbs9 bbs4 bbs4 bbs2 bbs2 bbs5 bbs5 itsn2a itsn2a itsn2b itsn2b copg2 copg2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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arl6ADP-ribosylation factor-like protein 6; Probably involved in membrane protein trafficking at the base of the ciliary organelle. May function in cilia biogenesis. Isoform 2 is required for proper retinal function and organization. Belongs to the small GTPase superfamily. Arf family. (186 aa)    
Predicted Functional Partners:
arl6ip1
ADP-ribosylation factor-like 6-interacting protein 1.
   
 
 0.882
bbs7
Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.
   
 0.678
bbs1
Bardet-Biedl syndrome 1.
   
 0.678
bbs9
Bardet-Biedl syndrome 9.
   
 0.630
bbs4
Bardet-Biedl syndrome 4.
   
 0.629
bbs2
Bardet-Biedl syndrome 2 protein homolog; Required for ciliogenesis.
   
 0.625
bbs5
Bardet-Biedl syndrome 5 protein homolog; Required for ciliogenesis; Belongs to the BBS5 family.
   
 0.591
itsn2a
Intersectin 2a.
    
 
 0.581
itsn2b
Intersectin 2b.
    
 
 0.581
copg2
Coatomer subunit gamma-2; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity); Belongs to the COPG family.
    
 
 0.576
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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