Mapk9 protein (Mus musculus) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	Mapk9	mitogen activated protein kinase 9; Responds to activation by environmental stress and pro- inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T- cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells (423 aa)
		(Mus musculus)
Predicted Functional Partners:
	Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3; The JNK-interacting protein (JIP) gro [...] (1337 aa)	•	•	•	0.991
	Jun	Jun oncogene; Transcription factor that recognizes and binds to the enhancer heptamer motif 5'- [...] (334 aa)	•	•	•	0.980
	Tnf	tumor necrosis factor; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly s [...] (235 aa)		•	•	0.955
	Map3k7ip1	mitogen-activated protein kinase kinase kinase 7 interacting protein 1; May be an important sig [...] (502 aa)		•	•	0.942
	Fos	FBJ osteosarcoma oncogene; Nuclear phosphoprotein which forms a tight but non- covalently linke [...] (380 aa)		•	•	0.936
	Traf6	Tnf receptor-associated factor 6; Adapter protein and signal transducer that links members of t [...] (530 aa)		•	•	0.936
	Tp53	transformation related protein 53; Acts as a tumor suppressor in many tumor types; induces grow [...] (378 aa)	•	•	•	0.932
	Bcl2l11	BCL2-like 11 (apoptosis facilitator); Induces apoptosis. The isoforms vary in cytotoxicity with [...] (196 aa)	•	•	•	0.929
	Jund	Jun proto-oncogene related gene d1 (308 aa)	•	•	•	0.924
	Map3k7ip2	mitogen-activated protein kinase kinase kinase 7 interacting protein 2; Regulates the IL1-media [...] (693 aa)		•	•	0.923

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Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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