version_number_image
 
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
aceK
Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity) (591 aa)
(Azoarcus sp. EbN1)
Predicted Functional Partners:
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophos [...] (208 aa)
       0.899
ebA5890
predicted UDP-N-acetylglucosamine 2-epimerase (378 aa)
       0.899
wbpI
UDP-N-acetylglucosamine 2-epimerase (385 aa)
       0.899
ebA4102
NUDIX hydrolase (313 aa)
       0.899
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis [...] (344 aa)
       0.899
ribE
Riboflavin synthase (Alpha chain) (201 aa)
       0.899
ribH
6,7-dimethyl-8-ribityllumazine synthase; Riboflavin synthase is a bifunctional enzyme complex c [...] (156 aa)
       0.899
thiL
Probable thiamine-monophosphate kinase protein (319 aa)
       0.899
aceA
Isocitrate lyase (433 aa)
     0.819
icd
Isocitrate dehydrogenase [NADP] (414 aa)
     0.734
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes         or: network depth