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This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
Ptprc
Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (T200) (CD45 antigen); Required for T-cell activation through the antigen receptor. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits an dephosphorylates SKAP1 and FYN (1172 aa)
(Rattus norvegicus)
Predicted Functional Partners:
Cd4
T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (W3/25 antigen); Ac [...] (457 aa)
    ••• 0.993
Lck
Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific pr [...] (509 aa)
    ••• 0.970
Cd247
CD3 antigen, zeta polypeptide (188 aa)
    ••• 0.959
ENSRNOG00000016069
annotation not available (189 aa)
     •• 0.952
ENSRNOG00000024000
annotation not available (852 aa)
    ••• 0.934
Cd3d
T-cell surface glycoprotein CD3 delta chain precursor (T-cell receptor T3 delta chain); The CD3 [...] (173 aa)
     •• 0.928
Lyn
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (512 aa)
    ••• 0.915
Cd3g
T-cell surface glycoprotein CD3 gamma chain precursor (T-cell receptor T3 gamma chain); The CD3 [...] (182 aa)
     •• 0.910
Hck
Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK) (Hemopoietic cell kinase); May serve as par [...] (524 aa)
     •• 0.908
Blk
B lymphoid kinase (499 aa)
     •• 0.907
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.
Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:
additional (white) nodes         or: network depth