STRINGSTRING
Abca13 Abca13 Abca8b Abca8b Abca5 Abca5 Abca8a Abca8a Abca9 Abca9 Abcd4 Abcd4 Abca4 Abca4 Abcf2 Abcf2 Gm11939 Gm11939 Abca17 Abca17 Abcc3 Abcc3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Abca13ATP-binding cassette sub-family A member 13. (5034 aa)    
Predicted Functional Partners:
Abca8b
ATP-binding cassette sub-family A member 8-B; ATP-dependent lipophilic drug transporter; Belongs to the ABC transporter superfamily. ABCA family.
   
 
0.697
Abca5
ATP-binding cassette sub-family A member 5; May play a role in the processing of autolysosomes.
    
 
0.683
Abca8a
ATP-binding cassette sub-family A member 8-A; ATP-dependent lipophilic drug transporter.
    
 
0.659
Abca9
ATP-binding cassette sub-family A member 9; May play a role in monocyte differentiation and lipid homeostasis; Belongs to the ABC transporter superfamily. ABCA family.
   
 
0.564
Abcd4
ATP-binding cassette sub-family D member 4; May be involved in intracellular processing of vitamin B12 (cobalamin). Could play a role in the lysosomal release of vitamin B12 into the cytoplasm (By similarity).
      
 0.555
Abca4
Retinal-specific phospholipid-transporting ATPase ABCA4; Catalyzes the translocation of specific phospholipids from the extracellular/lumenal to the cytoplasmic leaflet of membrane coupled to the hydrolysis of ATP. Transports preferentially phosphatidylethanolamine. In the visual cycle, acts as an inward- directed retinoid flipase, retinoid substrates imported by ABCA4 from the extracellular or intradiscal (rod) membrane surfaces to the cytoplasmic membrane surface are all-trans-retinaldehyde (ATR) and N- retinyl-phosphatidyl-ethanolamine (NR-PE). Once transported to the cytoplasmic su [...]
  
 
0.542
Abcf2
ATP-binding cassette sub-family F member 2; Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
      
 0.526
Gm11939
Predicted gene 11939.
      
 0.511
Abca17
ATP-binding cassette sub-family A member 17; Promotes cholesterol efflux from sperm which renders sperm capable of fertilization. Has also been shown to decrease levels of intracellular esterified neutral lipids including cholesteryl esters, fatty acid esters and triacylglycerols.
    
 
0.510
Abcc3
Canalicular multispecific organic anion transporter 2; May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes.
   
 
 0.483
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.