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  CSNK1E protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
CSNK1E
Casein kinase I isoform epsilon (EC 2.7.11.1) (CKI-epsilon) (CKIe); Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. May act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. Retains PER1 in the cytoplasm. Inhibits cytokine-induced granuloytic differentiation (416 aa)
(Homo sapiens)
Predicted Functional Partners:
AXIN1
Axin-1 (Axis inhibition protein 1) (hAxin); Controls dorsoventral patterning via two opposing e [...] (911 aa)
     0.998
PER2
Period circadian protein homolog 2 (Circadian clock protein PERIOD 2) (hPER2); Component of the [...] (1255 aa)
     0.997
PER3
Period circadian protein homolog 3 (Circadian clock protein PERIOD 3) (hPER3) (Cell growth-inhi [...] (1210 aa)
     0.995
PER1
Period circadian protein homolog 1 (Circadian clock protein PERIOD 1) (Circadian pacemaker prot [...] (1290 aa)
     0.992
ARNTL
Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (M [...] (627 aa)
     0.992
CRY1
Cryptochrome-1; Blue light-dependent regulator of the circadian feedback loop. Inhibits CLOCK|N [...] (586 aa)
     0.976
AKAP9
A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor prote [...] (3913 aa)
     0.976
CLOCK
Circadian locomoter output cycles protein kaput (hCLOCK); ARNTL/2-CLOCK heterodimers activate E [...] (846 aa)
      0.973
NPAS2
Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (Basic-helix [...] (824 aa)
      0.972
AXIN2
Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil); Inhibitor of the Wnt [...] (843 aa)
     0.970
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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