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  CACNA1C protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
CACNA1C
Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle); Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1C gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the [...] (2244 aa)
(Homo sapiens)
Predicted Functional Partners:
CACNB3
Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-depende [...] (484 aa)
     0.993
CACNA2D1
Dihydropyridine-sensitive L-type calcium channel subunits alpha- 2/delta precursor [Contains- L [...] (1091 aa)
     0.987
RYR2
Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ry [...] (4965 aa)
     0.972
CACNB2
Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-depende [...] (660 aa)
      0.956
CACNA1G
Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subun [...] (2377 aa)
     0.936
AKAP5
A-kinase anchor protein 5 (A-kinase anchor protein 79 kDa) (AKAP 79) (cAMP-dependent protein ki [...] (427 aa)
       0.932
CACNA1H
Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subun [...] (2353 aa)
     0.928
CACNA1E
Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subun [...] (2313 aa)
     0.920
ENSG00000160014
Calmodulin (CaM); Calmodulin mediates the control of a large number of enzymes and other protei [...] (149 aa)
      0.920
CACNA1B
Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subun [...] (2339 aa)
     0.920
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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