version_number_image
 
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
POFUT1
GDP-fucose protein O-fucosyltransferase 1 precursor (EC 2.4.1.221) (Peptide-O-fucosyltransferase 1) (O-FucT-1); Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in EGF domains. Plays a crucial role in Notch signaling (388 aa)
(Homo sapiens)
Predicted Functional Partners:
NOTCH1
Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated no [...] (2555 aa)
      0.930
PLAGL2
Zinc finger protein PLAGL2 (Pleiomorphic adenoma-like protein 2); Shows weak transcriptional ac [...] (496 aa)
       0.850
KIF3B
Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B) (HH0048); Involved [...] (747 aa)
       0.820
DLL1
Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1); Acts as a lig [...] (723 aa)
      0.819
JAG1
Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen); Ligand for multiple Notch receptors and inv [...] (1218 aa)
      0.797
NOTCH2
Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains- Notch 2 extracell [...] (2471 aa)
      0.777
RBPJ
Recombining binding protein suppressor of hairless (J kappa- recombination signal-binding prote [...] (500 aa)
       0.760
EGFLAM
EGF-like, fibronectin type III and laminin G domains isoform 3 (1017 aa)
       0.760
LFNG
Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta [...] (379 aa)
       0.759
POFUT2
GDP-fucose protein O-fucosyltransferase 2 precursor (EC 2.4.1.221) (Peptide-O-fucosyltransferas [...] (429 aa)
       0.726
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes         or: network depth