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This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
guaC
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity) (328 aa)
(Bacillus clausii)
Predicted Functional Partners:
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotid [...] (428 aa)
• •  •• 0.983
guaA
bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP fr [...] (515 aa)
• •• •• 0.981
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of A [...] (171 aa)
     •• 0.948
guaB
Inosine-5'-monophosphate dehydrogenase (485 aa)
  •• •••0.923
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP (By similarity) (205 aa)
     •• 0.915
hprT
Hypoxanthine-guanine phosphoribosyltransferase (179 aa)
     •• 0.901
ABC2957
5'-nucleotidase (448 aa)
     •  0.899
ABC1445
5'-nucleotidase (923 aa)
     •  0.899
purH
bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (511 aa)
     •  0.899
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic [...] (201 aa)
•     • 0.575
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.
Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:
additional (white) nodes         or: network depth