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Dnajc14 Dnajc14 Stk11ip Stk11ip Nrde2 Nrde2 Tbc1d10b Tbc1d10b Drd1 Drd1 Pdcl Pdcl Gimap8 Gimap8 Odr4 Odr4 Tmub2 Tmub2 Znf48 Znf48 Adora1 Adora1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Dnajc14DnaJ homolog subfamily C member 14; Regulates the export of target proteins, such as DRD1, from the endoplasmic reticulum to the cell surface. (703 aa)    
Predicted Functional Partners:
Stk11ip
Serine/threonine kinase 11-interacting protein.
   
  
 0.646
Nrde2
NRDE-2, necessary for RNA interference, domain-containing.
      
 0.633
Tbc1d10b
TBC1 domain family, member 10b (Predicted).
   
  
 0.625
Drd1
D(1A) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
    
 
 0.601
Pdcl
Phosducin-like protein; Functions as a co-chaperone for CCT in the assembly of heterotrimeric G protein complexes, facilitates the assembly of both Gbeta-Ggamma and RGS-Gbeta5 heterodimers. Acts also as a positive regulator of hedgehog signaling and regulates ciliary function. Belongs to the phosducin family.
   
  
 0.600
Gimap8
GTPase IMAP family member 8; Exerts an anti-apoptotic effect in the immune system and is involved in responses to infections.
      
 0.589
Odr4
Odr-4 GPCR localization factor homolog.
   
  
 0.569
Tmub2
Transmembrane and ubiquitin-like domain-containing protein 2.
   
  
 0.521
Znf48
RCG39517, isoform CRA_a.
      
 0.509
Adora1
Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.
   
  
 0.502
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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