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Myg1 Myg1 Mfsd5 Mfsd5 Ndufs8 Ndufs8 Gpalpp1 Gpalpp1 Kprp Kprp Pfdn5 Pfdn5 Ndufs2 Ndufs2 Ndufs1 Ndufs1 Xrra1 Xrra1 Sdha Sdha Sdhc Sdhc
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
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[Homology]
Score
Myg1UPF0160 protein MYG1, mitochondrial. (381 aa)    
Predicted Functional Partners:
Mfsd5
Major facilitator superfamily domain-containing 5.
   
  
 0.742
Ndufs8
NADH dehydrogenase (Ubiquinone) Fe-S protein 8 (Predicted), isoform CRA_a.
   
    0.715
Gpalpp1
GPALPP motifs-containing protein 1.
   
  
 0.714
Kprp
Keratinocyte proline-rich protein.
      
 0.711
Pfdn5
Prefoldin 5 (Predicted), isoform CRA_a.
   
  
 0.700
Ndufs2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
   
    0.683
Ndufs1
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized (By sim [...]
   
    0.667
Xrra1
X-ray radiation resistance-associated 1.
      
 0.660
Sdha
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor. Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
   
    0.656
Sdhc
Succinate dehydrogenase complex, subunit C, integral membrane protein, isoform CRA_b.
   
    0.654
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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