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This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
ispE
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) (292 aa)
(Bacillus licheniformis)
Predicted Functional Partners:
ispD
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosph [...] (231 aa)
    0.998
ispF
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Converts 4-diphosphocytidyl-2-C-methyl-D [...] (158 aa)
    0.997
purR
PurR (Transcriptional regulator) (277 aa)
       0.849
spoVG
Putative septation protein spoVG; Essential for sporulation. Interferes with or is a negative r [...] (97 aa)
       0.847
prs
Ribose-phosphate pyrophosphokinase (316 aa)
       0.835
rplY
50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome [...] (208 aa)
       0.823
glmU
Bifunctional protein glmU; Catalyzes the last two sequential reactions in the de novo biosynthe [...] (456 aa)
      0.816
ksgA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines in the loop of [...] (292 aa)
       0.816
pth
Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl- tRNAs which dro [...] (188 aa)
       0.813
dxr
1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and [...] (383 aa)
      0.789
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes         or: network depth