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This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
ESA1
Histone acetyltransferase ESA1; Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A.Z. Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, histone H2B to form H2BK16ac, and histone H2A to form H2AK4ac and H2AK7ac. Acetylation of histone H4 is essential for DNA double-strand break repair through homologous recombination. Involved in cell cycle progression. Recrui [...] (521 aa)
(Debaryomyces hansenii)
Predicted Functional Partners:
EAF3
Chromatin modification-related protein EAF3; Involved in deacetylation of histones, chromatin a [...] (316 aa)
     0.860
YNG2
Chromatin modification-related protein YNG2; Component of the NuA4 histone acetyltransferase co [...] (285 aa)
     0.855
ARP4
Actin-related protein 4; Chromatin interaction component of the NuA4 histone acetyltransferase [...] (492 aa)
     0.855
GCN5
Histone acetyltransferase GCN5; Acetylates histone H2B to form H2BK11ac and H2BK16ac, histone H [...] (455 aa)
     0.839
EPL1
Enhancer of polycomb-like protein 1; Component of the NuA4 histone acetyltransferase complex wh [...] (1016 aa)
     0.785
RBV1
RuvB-like helicase 1; DNA helicase which participates in several chromatin remodeling complexes [...] (457 aa)
     0.707
RVB2
RuvB-like helicase 2; DNA helicase which participates in several chromatin remodeling complexes [...] (480 aa)
     0.675
DEHA0B07986g
hypothetical protein (639 aa)
      0.651
DEHA0G13409g
hypothetical protein (255 aa)
      0.615
SPT16
FACT complex subunit SPT16; Component of the FACT complex, a general chromatin factor that acts [...] (1033 aa)
      0.613
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
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additional (white) nodes         or: network depth