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This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
ESA1
Histone acetyltransferase ESA1; Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A.Z. Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, histone H2B to form H2BK16ac, histone H2A to form H2AK4ac and H2AK7ac, and histone variant H2A.Z to form H2A.ZK14ac. Acetylation of histone H4 is essential for DNA double-strand break repair through homologous recombination. [...] (439 aa)
(Kluyveromyces lactis)
Predicted Functional Partners:
ARP4
Actin-related protein 4; Chromatin interaction component of the NuA4 histone acetyltransferase [...] (520 aa)
     0.908
EPL1
Enhancer of polycomb-like protein 1; Component of the NuA4 histone acetyltransferase complex wh [...] (806 aa)
     0.898
YAF9
Protein AF-9 homolog; Component of the SWR1 complex which mediates the ATP- dependent exchange [...] (220 aa)
     0.883
EAF3
Chromatin modification-related protein EAF3; Involved in deacetylation of histones, chromatin a [...] (358 aa)
     0.854
GCN5
Histone acetyltransferase GCN5; Acetylates histone H2B to form H2BK11ac and H2BK16ac, histone H [...] (516 aa)
     0.843
YNG2
Chromatin modification-related protein YNG2; Component of the NuA4 histone acetyltransferase co [...] (295 aa)
     0.837
SWC4
SWR1-complex protein 4; Component of the SWR1 complex which mediates the ATP- dependent exchang [...] (497 aa)
     0.813
KLLA0F22066g
KLLA0F22066p (3764 aa)
     0.794
EAF6
Chromatin modification-related protein EAF6; Component of the NuA4 histone acetyltransferase co [...] (115 aa)
      0.680
RVB1
RuvB-like helicase 1; DNA helicase which participates in several chromatin remodeling complexes [...] (457 aa)
     0.676
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes         or: network depth