version_number_image
 
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
DOT1
Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones (By similarity) (572 aa)
(Kluyveromyces lactis)
Predicted Functional Partners:
SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific; Histone methyltransferase that methy [...] (702 aa)
    • • 0.748
SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (S [...] (1000 aa)
    • • 0.735
KLLA0E18139g
KLLA0E18063p (326 aa)
    • • 0.636
RAD18
Postreplication repair E3 ubiquitin-protein ligase RAD18; E3 RING-finger protein, member of the [...] (427 aa)
    • • 0.605
KLLA0A01848g
KLLA0A01848p (645 aa)
    • • 0.584
KLLA0F00330g
KLLA0F00330p (370 aa)
    •   0.550
KLLA0D09482g
KLLA0D09482p (323 aa)
    •   0.548
KLLA0D02090g
KLLA0D02090p (602 aa)
    •   0.546
KLLA0E22517g
KLLA0E22419p (389 aa)
    • • 0.521
RAD5
DNA repair protein RAD5; Probable helicase, member of the UBC2/RAD6 epistasis group. Functions [...] (1114 aa)
    • • 0.518
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.
Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:
additional (white) nodes         or: network depth