DOT1 protein (Candida glabrata) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	DOT1	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones (By similarity) (652 aa)
		(Candida glabrata)
Predicted Functional Partners:
	SET2	Histone-lysine N-methyltransferase, H3 lysine-36 specific; Histone methyltransferase that methy [...] (716 aa)	•	•	0.761
	SET1	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (S [...] (1111 aa)	•	•	0.742
	CAGL0L09757g	Similar to uniprot\|P36104 Saccharomyces cerevisiae YKL018w (326 aa)	•	•	0.644
	RAD18	Postreplication repair E3 ubiquitin-protein ligase RAD18; E3 RING-finger protein, member of the [...] (411 aa)	•	•	0.641
	CAGL0I03256g	Strain CBS138 chromosome I complete sequence (362 aa)	•	•	0.613
	CAGL0F02959g	Similar to uniprot\|Q04049 Saccharomyces cerevisiae YDR419w RAD30 DNA repair protein (635 aa)	•	•	0.596
	CAGL0E05588g	Similar to uniprot\|P12689 Saccharomyces cerevisiae YOR346w REV1 DNA repair protein (887 aa)	•	•	0.584
	CAGL0J07216g	Strain CBS138 chromosome J complete sequence (390 aa)	•		0.567
	CAGL0K02453g	Similar to uniprot\|Q12495 Saccharomyces cerevisiae YPR018w CAC1 (584 aa)	•		0.561
	RAD5	DNA repair protein RAD5; Probable helicase, member of the UBC2/RAD6 epistasis group. Functions [...] (1151 aa)	•	•	0.556

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Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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