Hsd17b4 protein (Rattus norvegicus) - STRING interaction network

Hsd17b4 protein (Rattus norvegicus) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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	Hsd17b4	Peroxisomal multifunctional enzyme type 2 (MFE-2) (D-bifunctional protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) (D-3-hydroxyacyl-CoA dehydratase) (EC 4.2.1.107) (3-alpha,7- alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hy; Bifunctional enzyme acting on the peroxisomal beta- oxidation pathway for fatty acids. Catalyzes the formation of 3- ketoacyl-CoA intermediates from both straight-chain and 2-methyl- branched-chain fatty acids (By similarity) (751 aa)
		(Rattus norvegicus)
Predicted Functional Partners:
	Acox1	Acyl-coenzyme A oxidase 1, peroxisomal (EC 1.3.3.6) (Palmitoyl-CoA oxidase) (AOX) [Contains- Ac [...] (629 aa)	•	•	•	0.980
	Ehhadh	Peroxisomal bifunctional enzyme (PBE) (PBFE) [Includes- Enoyl-CoA hydratase/3,2-trans-enoyl-CoA [...] (722 aa)		•	•	0.977
	Acox2	Acyl-coenzyme A oxidase 2, peroxisomal (EC 1.17.99.3) (3-alpha,7- alpha,12-alpha-trihydroxy-5-b [...] (681 aa)		•	•	0.975
	Acox3	Acyl-coenzyme A oxidase 3, peroxisomal (EC 1.3.3.6) (Pristanoyl-CoA oxidase) (Branched-chain ac [...] (698 aa)		•	•	0.965
	Acaa1a	3-ketoacyl-CoA thiolase A, peroxisomal precursor (EC 2.3.1.16) (Beta- ketothiolase A) (Acetyl-C [...] (424 aa)		•	•	0.957
	Acaa2	3-ketoacyl-CoA thiolase, mitochondrial (EC 2.3.1.16) (Beta- ketothiolase) (Acetyl-CoA acyltrans [...] (392 aa)		•	•	0.952
	Echs1	Enoyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.17) (Short chain enoyl-CoA hydratase) (S [...] (290 aa)		•	•	0.922
	Acaa1b	3-ketoacyl-CoA thiolase B, peroxisomal precursor (EC 2.3.1.16) (Beta- ketothiolase B) (Acetyl-C [...] (422 aa)		•	•	0.917
	Hadha	Trifunctional enzyme subunit alpha, mitochondrial precursor (TP-alpha) [Includes- Long-chain en [...] (190 aa)		•	•	0.903
	Aldh3a2	Fatty aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde dehydrogenase, microsomal) (Aldehyde dehydr [...] (507 aa)		•		0.899

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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