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This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
CACNA1D
Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2); Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage a [...] (2181 aa)
(Homo sapiens)
Predicted Functional Partners:
CACNA2D1
Dihydropyridine-sensitive L-type calcium channel subunits alpha- 2/delta precursor [Contains- L [...] (1091 aa)
     •• 0.996
CACNG1
Voltage-dependent calcium channel gamma-1 subunit (Dihydropyridine- sensitive L-type, skeletal [...] (222 aa)
     •• 0.985
CACNB1
Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-depende [...] (599 aa)
     •• 0.985
CACNG8
Voltage-dependent calcium channel gamma-8 subunit (Neuronal voltage- gated calcium channel gamm [...] (425 aa)
     •• 0.984
CACNG7
Voltage-dependent calcium channel gamma-7 subunit (Neuronal voltage- gated calcium channel gamm [...] (275 aa)
     •• 0.984
CACNB2
Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-depende [...] (660 aa)
    ••• 0.981
CACNG6
Voltage-dependent calcium channel gamma-6 subunit (Neuronal voltage- gated calcium channel gamm [...] (260 aa)
     •• 0.981
CACNG3
Voltage-dependent calcium channel gamma-3 subunit (Neuronal voltage- gated calcium channel gamm [...] (315 aa)
     •• 0.980
CACNG4
Voltage-dependent calcium channel gamma-4 subunit (Neuronal voltage- gated calcium channel gamm [...] (327 aa)
     •• 0.968
CACNB3
Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-depende [...] (484 aa)
     •• 0.961
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.
Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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or custom value: or custom limit:
additional (white) nodes         or: network depth