CAMK2A protein (Homo sapiens) - STRING interaction network

CAMK2A protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	CAMK2A	Calcium/calmodulin-dependent protein kinase type II alpha chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II subunit alpha); CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity) (489 aa)
		(Homo sapiens)
Predicted Functional Partners:
	ENSG00000160014	Calmodulin (CaM); Calmodulin mediates the control of a large number of enzymes and other protei [...] (149 aa)	•	•	•	•	0.997
	GRIN2B	Glutamate [NMDA] receptor subunit epsilon-2 precursor (N-methyl D- aspartate receptor subtype 2 [...] (1484 aa)		•	•	•	0.997
	CREB1	cAMP response element-binding protein (CREB); This protein binds the cAMP response element (CRE [...] (341 aa)		•	•	•	0.995
	GRIA1	Glutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA [...] (906 aa)			•	•	0.985
	MAPT	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-ta [...] (776 aa)		•	•	•	0.978
	GRIN2A	Glutamate [NMDA] receptor subunit epsilon-1 precursor (N-methyl D- aspartate receptor subtype 2 [...] (1464 aa)		•	•	•	0.974
	SMAD2	Mothers against decapentaplegic homolog 2 (SMAD 2) (Mothers against DPP homolog 2) (Mad-related [...] (467 aa)		•	•	•	0.961
	DLG4	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90 [...] (767 aa)			•	•	0.959
	ACTN2	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein); F-ac [...] (894 aa)		•	•		0.959
	DLG1	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg); Essential multidomain sc [...] (926 aa)		•	•	•	0.958

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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