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This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
purK
Phosphoribosylaminoimidazole carboxylase ATPase subunit; Possesses an ATPase activity that is dependent on the presence of AIR (aminoimidazole ribonucleotide). The association of purK and purE produces an enzyme complex capable of converting AIR to CAIR efficiently under physiological condition (By similarity) (377 aa)
(Vibrio vulnificus YJ016)
Predicted Functional Partners:
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit; This subunit can alone transform AI [...] (161 aa)
  0.999
purM
Phosphoribosylformylglycinamidine cyclo-ligase (346 aa)
    0.973
VV2419
Glutamine phosphoribosylpyrophosphate amidotransferase (504 aa)
   0.947
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase (367 aa)
     0.937
purH
bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (530 aa)
     0.924
VV2516
Folate-dependent phosphoribosylglycinamide formyltransferase PurN (224 aa)
     0.905
purD
Phosphoribosylamine--glycine ligase (444 aa)
     0.904
thiC
Thiamine biosynthesis protein thiC; Required for the synthesis of the hydromethylpyrimidine (HM [...] (647 aa)
       0.800
purL
Phosphoribosylformylglycinamidine synthase (1351 aa)
     0.727
folD
Bifunctional protein folD; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-m [...] (285 aa)
      0.695
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes         or: network depth