STRING 9.1 
  VTCN1 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
VTCN1
V-set domain containing T cell activation inhibitor 1; Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor- associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation (282 aa)
(Homo sapiens)
Predicted Functional Partners:
BTLA
B and T lymphocyte associated; Lymphocyte inhibitory receptor which inhibits lymphocytes during [...] (289 aa)
      0.910
PDCD1
programmed cell death 1; Possible cell death inducer, in association with other factors (288 aa)
       0.569
CTLA4
cytotoxic T-lymphocyte-associated protein 4; Possibly involved in T-cell activation. Binds to B [...] (223 aa)
       0.423
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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