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  ENSMUSG00000046709 protein (Mus musculus) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
ENSMUSG00000046709
mitogen activated protein kinase 10; Responds to activation by environmental stress and pro- inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. Required for stress-induced neuronal apoptosis and the pathogenesis of glutamate excitotoxicity (464 aa)
(Mus musculus)
Predicted Functional Partners:
Mapk8ip3
mitogen-activated protein kinase 8 interacting protein 3; The JNK-interacting protein (JIP) gro [...] (1337 aa)
     0.988
Bcl2l11
BCL2-like 11 (apoptosis facilitator); Induces apoptosis. The isoforms vary in cytotoxicity with [...] (196 aa)
     0.946
Mapk8ip1
mitogen activated protein kinase 8 interacting protein 1; The JNK-interacting protein (JIP) gro [...] (707 aa)
     0.923
Bad
Bcl-associated death promoter; Promotes cell death. Successfully competes for the binding to Bc [...] (204 aa)
      0.918
Ngfr
nerve growth factor receptor (TNFR superfamily, member 16); Low affinity receptor which can bin [...] (427 aa)
      0.914
Map3k7ip1
mitogen-activated protein kinase kinase kinase 7 interacting protein 1; May be an important sig [...] (502 aa)
      0.911
Tlr3
toll-like receptor 3; Participates in the innate immune response to microbial agents. Mediates [...] (905 aa)
      0.907
Map3k7ip2
mitogen-activated protein kinase kinase kinase 7 interacting protein 2; Regulates the IL1-media [...] (693 aa)
      0.904
Map3k7
mitogen activated protein kinase kinase kinase 7; Component of a protein kinase signal transduc [...] (606 aa)
     0.903
Mapk8
mitogen activated protein kinase 8; Responds to activation by environmental stress and pro- inf [...] (427 aa)
    0.902
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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