node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADAL | VSIG10L | ENSP00000456242 | ENSP00000335623 | Adenosine deaminase-like protein; Catalyzes the hydrolysis of the free cytosolic methylated adenosine nucleotide N(6)-methyl-AMP (N6-mAMP) to produce inositol monophosphate (IMP) and methylamine. Is required for the catabolism of cytosolic N6-mAMP, which is derived from the degradation of mRNA containing N6-methylated adenine (m6A). Catalyzes the removal of different alkyl groups not only from N6-substituted purine or 2-aminopurine nucleoside monophosphates but also from O6-substituted compounds in vitro ; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deami [...] | V-set and immunoglobulin domain containing 10 like. | 0.414 |
ADAL | ZNF835 | ENSP00000456242 | ENSP00000444747 | Adenosine deaminase-like protein; Catalyzes the hydrolysis of the free cytosolic methylated adenosine nucleotide N(6)-methyl-AMP (N6-mAMP) to produce inositol monophosphate (IMP) and methylamine. Is required for the catabolism of cytosolic N6-mAMP, which is derived from the degradation of mRNA containing N6-methylated adenine (m6A). Catalyzes the removal of different alkyl groups not only from N6-substituted purine or 2-aminopurine nucleoside monophosphates but also from O6-substituted compounds in vitro ; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deami [...] | Zinc finger protein 835; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.439 |
CHD3 | VSIG10L | ENSP00000369716 | ENSP00000335623 | Chromodomain-helicase-DNA-binding protein 3; Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Required for anchoring centrosomal pericentrin in both interphase and mitosis, for spindle organization and centrosome integrity. | V-set and immunoglobulin domain containing 10 like. | 0.400 |
KIZ | VSIG10L | ENSP00000479542 | ENSP00000335623 | Centrosomal protein kizuna; Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole. Belongs to the kizuna family. | V-set and immunoglobulin domain containing 10 like. | 0.453 |
KIZ | ZSCAN26 | ENSP00000479542 | ENSP00000485228 | Centrosomal protein kizuna; Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole. Belongs to the kizuna family. | Zinc finger and SCAN domain-containing protein 26; May be involved in transcriptional regulation. | 0.419 |
MORN5 | VSIG10L | ENSP00000362869 | ENSP00000335623 | MORN repeat containing 5. | V-set and immunoglobulin domain containing 10 like. | 0.463 |
NBPF9 | VSIG10L | ENSP00000477979 | ENSP00000335623 | Neuroblastoma breakpoint family member 9; NBPF member 9; Belongs to the NBPF family. | V-set and immunoglobulin domain containing 10 like. | 0.422 |
SHROOM1 | VSIG10L | ENSP00000367950 | ENSP00000335623 | Protein Shroom1; May be involved in the assembly of microtubule arrays during cell elongation. | V-set and immunoglobulin domain containing 10 like. | 0.404 |
SLURP1 | VSIG10L | ENSP00000246515 | ENSP00000335623 | Secreted Ly-6/uPAR-related protein 1; Has an antitumor activity. Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin. In vitro down-regulates keratinocyte proliferation; the function may involve the proposed role as modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-7-dependent nAChR currents in an allosteric manner. In T cells may be involved in regulation of intracellular Ca(2+) signaling. Seems to have an immunomodulatory functi [...] | V-set and immunoglobulin domain containing 10 like. | 0.455 |
TCHHL1 | VSIG10L | ENSP00000357796 | ENSP00000335623 | Trichohyalin-like protein 1; Trichohyalin like 1; Belongs to the S-100 family. | V-set and immunoglobulin domain containing 10 like. | 0.404 |
VSIG10L | ADAL | ENSP00000335623 | ENSP00000456242 | V-set and immunoglobulin domain containing 10 like. | Adenosine deaminase-like protein; Catalyzes the hydrolysis of the free cytosolic methylated adenosine nucleotide N(6)-methyl-AMP (N6-mAMP) to produce inositol monophosphate (IMP) and methylamine. Is required for the catabolism of cytosolic N6-mAMP, which is derived from the degradation of mRNA containing N6-methylated adenine (m6A). Catalyzes the removal of different alkyl groups not only from N6-substituted purine or 2-aminopurine nucleoside monophosphates but also from O6-substituted compounds in vitro ; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deami [...] | 0.414 |
VSIG10L | CHD3 | ENSP00000335623 | ENSP00000369716 | V-set and immunoglobulin domain containing 10 like. | Chromodomain-helicase-DNA-binding protein 3; Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Required for anchoring centrosomal pericentrin in both interphase and mitosis, for spindle organization and centrosome integrity. | 0.400 |
VSIG10L | KIZ | ENSP00000335623 | ENSP00000479542 | V-set and immunoglobulin domain containing 10 like. | Centrosomal protein kizuna; Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole. Belongs to the kizuna family. | 0.453 |
VSIG10L | MORN5 | ENSP00000335623 | ENSP00000362869 | V-set and immunoglobulin domain containing 10 like. | MORN repeat containing 5. | 0.463 |
VSIG10L | NBPF9 | ENSP00000335623 | ENSP00000477979 | V-set and immunoglobulin domain containing 10 like. | Neuroblastoma breakpoint family member 9; NBPF member 9; Belongs to the NBPF family. | 0.422 |
VSIG10L | SHROOM1 | ENSP00000335623 | ENSP00000367950 | V-set and immunoglobulin domain containing 10 like. | Protein Shroom1; May be involved in the assembly of microtubule arrays during cell elongation. | 0.404 |
VSIG10L | SLURP1 | ENSP00000335623 | ENSP00000246515 | V-set and immunoglobulin domain containing 10 like. | Secreted Ly-6/uPAR-related protein 1; Has an antitumor activity. Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin. In vitro down-regulates keratinocyte proliferation; the function may involve the proposed role as modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-7-dependent nAChR currents in an allosteric manner. In T cells may be involved in regulation of intracellular Ca(2+) signaling. Seems to have an immunomodulatory functi [...] | 0.455 |
VSIG10L | TCHHL1 | ENSP00000335623 | ENSP00000357796 | V-set and immunoglobulin domain containing 10 like. | Trichohyalin-like protein 1; Trichohyalin like 1; Belongs to the S-100 family. | 0.404 |
VSIG10L | ZNF835 | ENSP00000335623 | ENSP00000444747 | V-set and immunoglobulin domain containing 10 like. | Zinc finger protein 835; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.403 |
VSIG10L | ZSCAN26 | ENSP00000335623 | ENSP00000485228 | V-set and immunoglobulin domain containing 10 like. | Zinc finger and SCAN domain-containing protein 26; May be involved in transcriptional regulation. | 0.453 |